פרופ' ז'ון-פאול (משה) ללוש

פרופ'
פרופ' מן המנין, ראש המחלקה
פרופ' ז'ון-פאול (משה) ללוש
טלפון: 
פקס: 
דוא"ל: 
משרד: 
שעות קבלה: 

קורות חיים

1979: Engineer in Organic Chemistry (7th/52), ESCIL (Ecole Supérieure de Chimie Industrielle de Lyon), Claude Bernard University, La Doua, Lyon (France)

1981: Engineer-Doctor in Organic Chemistry (Diplôme d' Ingénieur-Docteur), Claude Bernard University, La Doua, Lyon (France)

1997: Guastalla Fellowship (Rachi Foundation), Associate Professor, the Ben-Gurion University of the Negev, the Institute for Applied Biosciences, Beer-Sheva, Israel

2000: Associate Professor, Department of Chemistry, Nanomaterials Research Center, Institute of Nanotechnology & Advanced Materials, Bar-Ilan University, Ramat-Gan, Israel

2008-onwards: Full Professor, Department of Chemistry, Nanomaterials Research Center, Institute of Nanotechnology & Advanced Materials, Bar-Ilan University, Ramat-Gan, Israel

 

Email:lellouj@biu.ac.il & jp.m.lellouche@gmail.com

פירסומים

Since 2004:​​​​​​​

  1. J.-P. Lellouche, N. Perlman, A. Joseph, S. Govindaraji, L. Buzhansky, Aline Yakir and Ian Bruce, New Magnetically Responsive Polydicarbazole-Magnetite Nanoparticles, Chem. Commun. 2004, (5), 560-561
  2. J.-P. Lellouche, and V. Kotlyar, Vilsmeier-Haack Reagents. Novel Electrophiles for the One-Step Formylation of O-Silylated Ethers to O-Formates, Synlett, 2004, (3), 564-571
  3. G. Garcia-Belmonte, Z. Pomerantz, J. Bisquert, J.-P. Lellouche, and A. Zaban, Analysis of ion diffusion in electronically conducting polydicarbazole films by impedance methods, Electrochim. Acta, 2004, 49, 3413-3417
  4. A. del Campo, T. Sen, J.-P. Lellouche, and I. J. Bruce, Multifunctional Magnetite and Silica-Magnetite Nanoparticles: Synthesis, Surface Activation and Applications in Life Sciences, J. Magn. Magn. Mater., 2005, 293, 33-40
  5. J.-P. Lellouche, S. Govindaraji, A. Joseph, J. Jang, K. Jin Lee, Polydipyrrole- and polydicarbazole-nanorods as new nanosized supports for DNA hybridization, Chem. Commun. 2005, 34, 4357-4359
  6. J.-P. Lellouche, S. Govindaraji, A. Joseph, L. Buzhansky, I. Bruce, E. Bauminger, J. Schlesinger, Magnetically Responsive Carboxylated Magnetite-Polydipyrrole/Polydicarbazole Nanocomposites of a Core-Shell Morphology. Preparation, Characterization and Use in DNA Hybridization, J. Amer. Chem. Soc., 2005, 127, 11998-12006
  7. Vadim Kotlyar, Lior Shahar, and J.-P. Lellouche, A Simple Homemade Reaction Station for Use in Parallel Solution-Phase Synthesis. Optimization of a Regioselective One-Step Deprotective O-Formylation Reaction Mediated by the Vilsmeier-Haack Reagent POCl3•DMF, Mol. Diversity, 2006, 10, 255-264
  8. S. Govindaraji, P. Nakache, V. Marks, Z. Pomerantz, A. Zaban, and J.-P. Lellouche, Novel Carboxylated Pyrrole- and Carbazole-Based Monomers. Synthesis and Electro-Oxidation Features, J. Org. Chem., 2006, 71, 9139-9143
  9. Z. Pomerantz, G. Garcia-Belmonte, J.-P. Lellouche, A. Joseph, J. Bisquert, A. Zaban, The effect of Ion-Polymer Binding on Ionic Diffusion in Dicarbazole-Based Conducting Polymers, Electrochim. Acta, 2007, 52, 6841-6847
  10. M.-A. Neouze, M. Malenovska, U. Schubert, V. Kotlyar, E. Kuperschmidt, A. Peled, and J.-P. Lellouche, Silica Nanoparticles with a Hybrid Organic-Inorganic Shell, J. Mater. Chem., 2008, 18, 121-125
  11. Z. Pomerantz, A. Zaban, S. Ghosh, J.-P. Lellouche, G. Garcia-Belmonte, J. Bisquert, Capacitance, Spectroelectrochemistry and Conductivity of Polarons and Bipolarons in a Polydicarbazole-Based Conducting Polymer, J. Electroanal. Chem., 2008, 614, 49-60
  12. J.-P. Lellouche, M. Piran, L. Shahar, J. Grinblat, and C. Pirlot, A Reversible Functional Decoration of Multi-Walled Carbon Nanotubes (MWCNTs) by Acyclic h4-(1E,3E)-Dienyl-Fe(CO)3 Complexes, J. Mater. Chem., 2008, 18, 1093-1099
  13. M. Malenovska, M.-A. Neouze, U. Schubert, A. Peled, and J.-P. Lellouche, Multi-Component Hybrid Organic-Inorganic Particles with Highly Dispersed Silver Nanoparticles in the External Shell, Dalton Trans. 2008, (34), 4647-4651
  14. M. Malenovska, M. Litschauer, M.-A. Neouze, U. Schubert, A. Peled, and J.-P. Lellouche, Multi-Component Hybrid Inorganic-Organic-Inorganic Particles with Various Metal Oxide Outer Shells, J. Organomet. Chem., 2009, 694, 1076–1080
  15. A. Peled, V. Kotlyar, and J.-P. Lellouche, A New Method for the Preparation of Silica-Polycarbazole Composite Particles of a Core-Shell Morphology, J. Mater. Chem., 2009, 19, 268-273
  16. M. Piran, V. Kotlyar, D. D. Medina, D. Goldman, C. Pirlot, and J.-P. Lellouche, End-Selective Functionalization of Carbon Nanotubes. Use of DOE for the Optimization of a DNA Probe Attachment and Hybridization Using an Enzymatic Amplifying System, J. Mater. Chem., 2009, 19, 631-638
  17. N. Esman, and J.-P. Lellouche, Fabrication of Functional Polypyrrole (PolyPyr)-Nanotubes Using Anodized Aluminium Oxide (AAO) Template Membranes. Compromising between Effectiveness and Mildness of Template Dissolution Conditions for a Safe Release of PolyPyr-Nanotubes, Polym. Chem., 2010, 1, 158–160
  18. D. Goldman and J.-P. Lellouche, An easy method for the production of functional polypyrrole/MWCNT and polycarbazole/MWCNT composites using nucleophilic multi-walled carbon nanotubes, Carbon, 2010, 48, 4170-77
  19. A. H. Haviv, J.-M. Grenèche, and J.-P. Lellouche, Aggregation Control of Hydrophilic Maghemite (g-Fe2O3) Nanoparticles by Surface Doping Using Cerium Atoms, J. Amer. Chem. Soc., 2010, 132, 12519-12521
  20. M. Naddaka, E. Mondal, and J.-P. Lellouche, Oxidative Fabrication of Spherical Polycarbazole-Based Microparticles, Mater. Lett., 2011, 65, 1165-67
  21. Y. Boguslavsky, T. Fadida, Y. Talyosef, and J.-P. Lellouche, Controlling the wettability of polyester fibers using grafted functional nanomaterials, J. Mater. Chem., 2011, 21(28), 10304-10310
  22. M. Naddaka, F. Asen, S. Freza, M. Bobrowski, P. Skurski, E. Laux, J. Charmet, H. Keppner, M. Bauer, and J.-P. Lellouche, Functionalization of Parylene during its chemical vapor deposition, J. Polym. Sci. Part A: Polym. Chem., 2011, 49, 2952-58
  23. A. Peled, M. Naddaka, and J.-P. Lellouche, Smartly designed photo-reactive silica nanoparticles and their reactivity, J. Mater. Chem, 2011, 21, 11511-17
  24. N. Esman, A. Haviv, and J.-P. Lellouche, Magnetically Responsive Polypyrrole Nanotubes Using Ce(III)-Stabilized Maghemite Nanoparticles, Nanotechnology, 2011, 22(28)
  25. D. Goldman, O. Girshevitz, and J.-P. Lellouche, AFM characterization of polydicarbazole-multi-walled carbon nanotube composites, J. Adv. Microscopy Res., 2011, 6(3), 215-222
  26. M. Alesker, A. Heller, Z. Malik, I. Makarovsky, and J.-P. Lellouche, Hybrid silica nanoparticles traceable by fluorescence and FT-IR spectroscopy: preparation, characterization, and preliminary biological studies, J. Mater. Chem., 2011, 21(29), 10883-10893
  27. M. Naddaka, E. Mondal, and J.-P. Lellouche, Preparation of Novel Photoreactive Polycarbazole-Based Microparticles: Reactivity Features, J. Polymer Sci. Part A: Polym. Chem., 2011, 49(21), 4687-4693
  28. I. Makarovsky, Y. Boguslavsky, M. Alesker, J. Lellouche, E. Banin, and J.-P. Lellouche, Novel Triclosan-Bound Hybrid Silica Nanoparticles and Their Enhanced Antimicrobial Properties, Adv. Funct. Mater., 2011, 21(22), 4295-4304
  29. J.-P. Lellouche, Z. Pomerantz, A. Zaban, R. Persky, H. E. Gottlieb, and S. Ghosh, Star-Shaped Dendritic Molecules Based on Carboxylated Carbazole and Pyrrole as Peripheral Units, Synth. Met., 2011, 161, 2378-2383
  30. J.-P. Lellouche, Z. Pomerantz, and S. Ghosh, Towards hybrid carbazole-pyrrole-based carboxylated monomers: chemical synthesis, characterization, and electro-oxidation properties, Tetrahedron Lett., 2011, 52(51), 6903-6907
  31. J. Lellouche, A. Friedman, J.-P. Lellouche, A. Gedanken, and E. Banin, Improved antibacterial and anti-biofilm activity of magnesium fluoride nanoparticles obtained by water-based ultrasound chemistry, Nanomedicine (Nanotechnology, Biology, and Medicine), 2012, 8(5), 702-711
  32. N. Esman, A. Peled, R. Ben-Ishay, Y. Kapp-Barnea, I. Grigoriants, and J.-P. Lellouche, Multi-functional silica nanotubes as a versatile nanoscale component for biology-driven sensing applications, J. Mater. Chem., 2012, 22(5), 2208-2214
  33. A. Peled, and J.-P. Lellouche, Preparation of a novel functional SiC@polythiophene nanocomposite of a core-shell morphology, J. Mater. Chem., 2012, 22, 5
  34. N. Lachman, Y. Harel, A. Green, N. Luster, J-P. Lellouche, and H. D. Wagner, Effect of scale and surface chemistry on the mechanical properties of carbon nanotube-based composites, J. Polymer Science, Part B: Polymer Physics, 2012, 50(14), 957-962
  35. A. Peled, and J.-P. Lellouche, Controllable Photodeposition of Metal Nanoparticles on a Photoreactive Silica Support, J. Mater. Chem., 2012, 22(15), 7580-83
  36. I. Makarovsky, Y. Boguslavsky, J. Lellouche, E. Banin, and J.-P. Lellouche, An Increased Efficiency of Triclosan Delivery by Novel Acrylate-Based Nanoparticles, Journal of Nanomedicine & Nanotechnology, 2012, S:11
  37. T. Fadida, and J.-P. Lellouche, Preparation and Characterization of Composites Built of Poly(N-Benzophenoyl Methacrylamide-co-N-Hydroxyethyl Acrylamide) Cores and Silica Raspberry-Like Shells with Dual Orthogonal Functionality, Journal of Colloid and Interface Science, 2012, 386(1), 167-173
  38. T. Fadida, and J.-P. Lellouche, Poly-N-(4-benzoylphenyl)methacrylamide Nanoparticles: Preparation, Characterization, and Photoreactivity Features, J. Polymer Research, 2012, 19(12), 1-12
  39. E. Locatelli, G. Larraitz, L. L. Israel, L. Passoni, M. Naddaka, A. Pucci, T. Reese, V. Gómez-Vallejo, P. Milani, M. Matteoli, J. Llop, J.-P. Lellouche, and M. C. Franchini, Biocompatible nanocomposite for PET/MRI hybrid imaging, Inter. J. Nanomedicine, 2012, 7, 6021-6033
  40. Y. Harel, S. Azoubel, S. Magdassi, and J.-P. Lellouche, A Dispersability Study on Poly(thiophen-3-yl-acetic acid) and PEDOT Multi-Walled Carbon Nanotube Composites using an Analytical Centrifuge, Journal of Colloids & Interface Science, 2013, 390, 62-69
  41. I. Makarovsky, J. Lellouche, J.-P. Lellouche, and E. Banin, Improved Triclosan Delivery by a Novel Silica-Based Nanocomposite, Adv. Healthcare Mater., 2013, 2(4), 607-19
  42. J.-P. Lellouche, R. R. Koner, and S. Ghosh, N-Substituted carbazole heterocycles and derivatives as multipurpose chemical species: at the interface of chemical engineering, polymer and materials science, Rev. Chem. Eng., 2013, 29(6), 413-437
  43. J. Vandooren, N. Berghmans, C. Dillen, I. Van Aelst, I. Ronsse, L. Limor Israel, I. Rosenberger, J. Kreuter, J.-P. Lellouche, S. Michaeli, M. Comes Franchini, M. Aiertza, D. R. Edwards, L. Shenkman, & G. Opdenakker, Intradermal air pouch leukocytosis as an in vivo test for nanoparticles, International J. Nanomedicine, 2013, 8, 4745-56
  44. Y. Kapilov Buchman, E. Lellouche, S. Zigdon, M. Bechor, S. Michaeli, & J.-P. Lellouche, Silica nanoparticles and Polyethyleneimine (PEI)-Mediated Functionalization: A new method of PEI covalent attachment for siRNA delivery applications, Bioconj. Chem., 2013, 24(12), 2076-87
  45. G. Mechrez, M. Krepner, Y. Ashkenazi, J.-P. Lellouche, and E. Sigal, Biocatalytic carbon nanotube paper: A “one-pot” route for fabrication of enzyme-immobilized membranes for organophosphates bioremediation, J. Mater. Chem. B: Materials for Biology & Medicine, 2014, 2(7), 915-922
  46. S. Kumar, S. Krishankanth, J. Mathew, Z. Pomerantz, J.-P. Lellouche, & S. Ghosh, Effect of N-α substitution on the electropolymerization of N-substituted pyrroles: Structure-reactivity relationship studies, J. Phys. Chem. C., 2014, 118(5), 2570-2579
  47. T. Nahum, H. Dodiuk, A. Dotan, S. Kenig, and J.-P. Lellouche, Durable bonding of silica nanoparticles to polymers by photoradiation for control of surface properties, Polym. Adv. Technol., 2014, 25(7), 723-731
  48. E. Chapnik, N. Rivkin, A. Mildner, G. Beck, R. Pasvolsky, E. Metzi-Raz, Y. Birger, G. Amir, I. Tirosh, Z. Porat, L. Israel, E. Lellouche, S. Michaeli, J.-P. Lellouche, S. Izraeli, S. Jung, E. Hornstein, mir-142 Orchestrates a Network of Actin Cytoskeleton Regulators During Magakaryopoiesis, eLife, 2014, 3:e01964, 1-22
  49. T. Nahum, H. Dodiuk, A. Dotan, S. Kenig & J.-P. Lellouche, Superhydrophobic Durable Coating based on UV-Photoreactive Silica Nanoparticles, J. Appl. Polym. Sci., 2014, 131(23), 41122-41128
  50. Y. Harel & J.-P. Lellouche, Dual/Multiphase MWCNT-Antimony-Doped Tin Oxide (ATO) Nanoparticles Composites: an Effective Covalent Fabrication Approach, J. Nanoparticle Res., 2014, 16(8), 1-14
  51. D. Raichman, D. Strawser, & J.-P. Lellouche, Design of Experiments: Optimizing the Polycarboxylation/functionalization of Tungsten Disulfide Nanotubes, Inorganics, 2014, 2(3), 455-467  L. L. Israel, E. Lellouche, R. S. Kenett, O. Green, S. Michaeli, and J.-P. Lellouche, Ce3/4+-Cation-Functionalized Maghemite Nanoparticles Towards siRNA-Mediated Gene Silencing, J. Mater. Chem. B, 2014, 2, 6215-6225
  52. I. Rosenberger, C. Schmithals, J. Vandooren, S. Bianchessi, P. Milani, E. Locatelli, L. L. Israel, F. Hübner, M. Matteoli, J.-P. Lellouche, M. Comes Franchini, L. Passoni, E. Scanziani, G. Opdenakker, A. Piiper, & J. Kreuter, Physico-Chemical & Toxicological Characterization of Iron-Containing Albumin Nanoparticles as Platforms for Medical Imaging, J. of Controlled Release, 2014, 194, 130-137
  53. O. Ravid-Hermesh, N. Zurgil, Y. Shafran, M. Sobolev, M. Galmidi, Y. Badihi, L. L. Israel, J.-P. Lellouche, E. Lellouche, S. Michaeli, & M. Deutsch, Real time quantification of protein expression and translocation at individual cell resolution using imaging-dish based live cell array, Analytical & Bioanalytical Chemistry, 2014, 406(28), 7085-7101
  54. D. Raichman, D. Strawser, and J.-P. Lellouche, Covalent Functionaliza-tion/Polycarboxylation of Tungsten Disulfide Inorganic Nanotubes (INTs-WS2), Nano Research , 2015, 8(5), 1454-1463
  55. L. L. Israel, E. I. Kovalenko, A. A. Boyko, A. M. Sapozhnikov, I. Rosenberger, J. Kreuter, L. Passoni, & J.-P. Lellouche, Towards Hybrid Biocompatible Magnetic rHuman Serum Albumin-Based Nanoparticles: Use of Ultra-Small [CeLn]3/4+ Cation-Doped Maghemite Nanoparticles as Functional Shell, Nanotechnology, 2015, 26(4), 45601
  56. R. B. Binyamini, Y. Boguslavsky, E. Laux, H. Keppner, and J.-P. Lellouche, A Simple One-Step Approach to the decoration of Parylene C Coatings Using Functional Silica-Based Nanoparticles, Surface & Coatings Technology, 2015, 263, 36-43
  57. M. Shilo, A. Sharon, M. Motiei, J.-P. M. Lellouche, & R. Popovtzer, The Effect of Nanoparticle Size on the Probability to Cross the Blood Brain Barrier, J. of Nanobiotechnology, 2015, 13, 19
  58. R. Ben-Ishay, Y. Kapp-Barnea, Irena Grigoriantz, E. Teblum, and J.-P. Lellouche, Real-time Acoustic Profiling of a Live Cancerous Cell Monolayer Using QCM, Sensors and Actuators, B: Chemicals, 2015, 215, 373-381
  59. E. Mondal, J.-P. Lellouche, & M. Naddaka, Novel carbazole (Cbz)-based carboxylated functional monomers: design, synthesis and characterization, ChemistryOpen, 2015, 4(4), 489-496
  60. Y. Kapilov-Buchman, E. Lellouche, S. Michaeli, & J.-P Lellouche, Unique surface modification of silica nanoparticles with polyethyleneimine (PEI) for siRNA delivery using cerium cation coordination chemistry, Bioconjugate Chem., 2015, 26(5), 880-889
  61. P. M. Nanikashvili, Y. Kapilov Buchman, L. L. Israel, J.-P. Lellouche, D. Zitoun, A. V. Butenko, & E. Sloutskin, Layering in sedimenting nanoparticle suspensions: the order-inducing role of randomness, Colloids & Surfaces, A: Physicochemical and Engineering Aspects, 2015, 483, 248-256
  62. E. Lellouche, L. L. Israel, M. Bechor, S. Attal, E. Kurlander, V. A Asher, A. Dolitzky, L. Shaham, S. Izraeli, J.-P. Lellouche, & S. Michaeli, MagRET nanoparticles: an iron oxide nanocomposite platform for gene silencing from microRNAs to long non-coding RNAs, Bionconjugate Chemistry, 2015, 26(8), 1692-1701
  63. S. Ostrovsky, M. J. Larsen, A. Peled, & J.-P. Lellouche, Photochemically modified ATO NPs as conductive electrocatalysts for proton exchange membrane (PEM) fuel cells, J of Nanopart. Res., 2015, 17(6), 1-16
  64. L. L. Israel, E. Lellouche, S. Ostrovsky, V.Yarmiayev, M. Bechor, S. Michaeli, and J.-P. Lellouche, Acute in vivo toxicity mitigation of magnetically responsive PEI-coated maghemite nanoparticles using controlled oxidation and surface modifications towards siRNA delivery, ACS Applied Materials & Interfaces, 2015, 7(28), 15240-15255
  65. I. Rosenberger, A. Strauss, S. Dobiasch, C. Weis, S. Szanyi, L. Gil-Iceta, E. Alonso, M. G. Esparza, V. Gómez-Vallejo, B. Szczupak, S. Plaza-García, S. Mirzaei, L. L. Israel, S. Bianchessi, E. Scanziani, J.-P. Lellouche, P. Knoll, J. Werner, K. Felix, L. Grenacher, T. Reese, J. Kreuter, & M. Jiménez-González, Targeted diagnostic magnetic nanoparticles for medical imaging of pancreatic cancer, Journal of Controlled Release, 2015, 214, 76-84
  66. L. L. Israel, F. Karimi, S. Bianchessi, E. Scanziani, L. Passoni, M. Matteoli, B. Langström, & J.-P. Lellouche, Surface Metal Cation Doping of Maghemite (γ-Fe2O3) Nanoparticles: Modulation of MRI Relaxivity Features and Chelator-Free 68Ga-Radiolabelling for Dual MRI-PET Imaging, Mater. Res. Express, 2015, 2(9), 1-14
  67. J. Zou, S. Ostrovsky, L. L. Israel, J.-P. Lellouche, & I. Pyykkö, Targeted Delivery of Contrast Agents to the Tympanic Medial Wall at Minimum Amount and the Efficient Uptake in the Inner Ear through Oval and Round Windows, Austin J. Radiology, 2015, 2(6), 1034
  68. D. Raichman, R. Ben-Shabat Binyamini, & J.-P. Lellouche, A new polythiophene-driven coating method on inorganic INT/IF-WS2 nanomaterial surface, RSC Advances, 2016, 6(6), 4490-4504
  69. C. Adams, L. L. Israel, S. Ostrovsky, A. Taylor, H. Poptani, J.-P. Lellouche, & D. Chari, Development of Multifunctional Magnetic Nanoparticles for Genetic Engineering and Tracking of Neural Stem Cells, Adv. Health Care Mater., 2016, 5(7), 841-849
  70. R. Ben Ishay, L. L Israel, E. Levy Eitan, D. Partouche, & J.-P. Lellouche, Maghemite-Human Serum Albumin Hybrid Nanoparticles: Towards a Theranostic System with High MRI r2* Relaxivity, J. Mater. Chem B: Materials for Biology & Medicine, 2016, 4(21), 3801
  71. S. Ostrovsky, S. Hahnewald, R. Kiran, P. Mistrik, R. Hessler, A. Tscherter, P. Senn, J. Kang, J. Kim, M. Roccio, & J.-P. Lellouche, Conductive Hybrid Carbon Nanotube (CNT)-polythiophene coatings for Innovative Auditory Neuron-Multi-Electrode Array Interfacing, RSC Advances, 2016, 6(48), 41714-41723
  72. L. L. Israel, E. Lellouche, M. Bechor, J. M. Grenèche, S. Michaeli, & J.-P. Lellouche, Ultrasound-Mediated Surface Engineering of Theranostic Magnetic Nanoparticles: An Effective One-Pot Functionalization Process Using Mixed Polymers for siRNA Delivery, J. of Nanomedicine & Nanotechnology, 2016, 7(3), 385
  73. H. Sade & J.-P. Lellouche, Functionalization of WS2 nanotubes with a conformal humin-like shell, Advanced Materials Interfaces, 2016, 3(20), 1600307
  74. B. Grünwald, J. Vandooren, E. Locatelli, P. Fiten, G. Opdenakker, P. Proost, A. Krüger, J.-P. Lellouche, L. L. Israel, L. Shenkman, & M. C. Franchini, Matrix Metalloproteinase-9 (MMP-9) as an activator of nanosystems for targeted drug delivery in pancreatic cancer, J. Controlled Release, 2016, 239, 39-48
  75. R. Ben Ishay, Y. Harel, R. Lavi, & J.-P. Lellouche, Multiple Functionalization of Tungsten Disulfide Inorganic Nanotubes by Covalently Grafted Conductive Polythiophenes, RSC Advances, 2016, 6(92), 89585-89598
  76. S. Dobiasch, S. Szanyi, A. Kjaev, J. Werner, A. Strauss, C. Weis, L. Grenacher, K. Kapilov-Buchman, L. L. Israel, J.-P. Lellouche, E. Locatelli, M. C. Franchini, J. Vandooren, G. Opdenakker, & K. Felix, Synthesis and functionalization of protease-activated nanoparticles with tissue plasminogen activator peptides as targeting moiety and diagnostic tool for pancreatic cancer, Journal of Nanobiotechnology, 2016, 14, 81
  77. J. Zou, S. Ostrovsky, L. L. Israel, H. feng, M. I. Kettunen, J.-P. Lellouche, & I. Pyykköe, Efficient Penetration of Ceric Ammonium Nitrate Oxidant-stabilized Gamma-maghemite Nanoparticles through the Oval and Round Windows into Rat Inner Ear Demonstrated by MRI, Journal of Biomedical Materials Research, Part B: Applied Biomaterials, 2017, 105(7), 1883-1891
  78. A. Munder, L. L. Israel, S. Kahremany, R. Binyamini, C. Zhang, M. Kolitz-Domb, O. Viskind, S. Zozulya, A. Levine, H. Senderowitz, S. Chessler, J.-P. Lellouche, & A. Gruzman, Mimicking Neuroligin-2 Functions in β-cells by Functionalized Nanoparticles as a Novel Approach for Antidiabetic Therapy, ACS Applied Materials & Interfaces, 2017, 9(2), 1189-1206
  79. S. Nandi, S. K. Bhunia, M. Pour, I. Nachman, D. Raichman, J.-P. Moshe Lellouche, &  R. Jelinek, Bifunctional Carbon-dot-WS2 Nanorods for Photothermal Therapy and Cell Imaging, Chemistry – A European Journal, 2017, 23(4), 963-969
  80. E. Lellouche, E. Locatelli, L. L. Israel, M. Naddaka, E. Kurlander, S. Michaeli, J.-P. Lellouche, & M. Comes-Franchini, Maghemite-Containing PLGA-PEG-Based Polymeric Nanoparticles for siRNA delivery: Toxicity and Silencing Evaluation, RSC Advances, 2017, 7(43), 26912-26920
  81. P. Senn, M. Roccio, S. Hahnewald, C. Frick, M. Kwiatkowska, M. Ishikawa, P. Bako, H. Li, F. Edin, W. Liu, H. Rask-Andersen, I. Pyykkö, J. Zou, M. Mannerström, H. Keppner, A. Homsy, E. Laux, M. Llera, J.-P. Lellouche, S. Ostrovsky, E. Banin, A. Gedanken, N. Perkas, U.Wank, K.-H. Wiesmüller, P. Mistrík, H. Benav, C. Garnham, C. Jolly, F. Gander, P. Ulrich, M. Müller, & H. Löwenheim, NANOCI - Nanotechnology Based Cochlear Implant With Gapless Interface to Auditory Neurons, Otology & Neurotology, 2017, 38(8), e224-e231
  82. C. G. Sokolik, R. Ben-Shabat Binyamini, A. Gedanken, & J.-P. Lellouche, Proteinaceous microspheres as a delivery system for carvacrol and thymol in antibacterial applications, Ultrasonics Sonochemistry, 2018, 41, 288-296
  83. J. Zou, B. Peng, S. Ostrovsky, B. Li, C. Li, M. I. Kettunen, J.-P. (Moshe) Lellouche, & I. Pyykkö, Biological effect tetra-branched anti-TNF-peptide and coating ratio-dependent penetration of the peptide-conjugated Cerium3/4+ Cation-stabilized gamma-maghemite nanoparticles into rat inner ear after transtympanic injection visualized by MRI – Journal of Materials Science & Nanotechnology, 2017, 5, 2
  84. H. Sade, A. Moshkovich, J.-P. Lellouche, & L. Rapoport, Testing of WS2 Nanoparticles Functionalized by a Humin-Like Shell as lubricant additives, Lubricants, 2018, 6(1), 3
  85. H. Sade, & J.-P. Lellouche, Preparation and Characterization of WS2@SiO2 and WS2@PANI Core-Shell Nanocomposites, Nanomaterials, 2018, 8(3), 156
  86. J. Laloy, H. Haguet, L. Alpan, D. Raichman, J. M. Dogné, & J.-P. Lellouche, Impact of Functional Inorganic Nanotubes f-INTs-WS2 on Hemolysis, Platelet Function, and Coagulation, Nano Convergence, 2018
  87. C. G. Sokolik & J.-P. Lellouche, Hybrid-Silica Nanoparticles as a Delivery System of the Natural Biocide Carvacrol, RSC Advances, 2018, 8(64), 36712-36721
  88. J. Zhang, H. Sade, Y. Zhao, A. T. Murdock, A. Bendavid, J.-P. Lellouche, G. Wang, & Z. Jun Han, Conformal carbon coating on WS2 nanotubes for excellent electrochemical performance of lithium-ion batteries, Nanotechnology, 2018, 30, 3
  89. T. Feczkó, A. Piiper, S. Ansar, F. W. Blixt, J.-P. Lellouche, L. L. Israel, & M. G. Wacker, Stimulating brain recovery after stroke using theranostic albumin nanocarriers loaded with nerve growth factor in combination therapy therapy, Journal of Controlled Release, 2018, 293, 63-72
  90. A. Munder, Y. Moskovitz, A. Meir, L. Levy, S. Kahremany, M. Kolitz-Domb, G. Cohen, E. Shtriker, O. Viskind, J.-P. Lellouche, H. Senderowitz, S. D. Chessler, E. E. Korshin, S. Ruthstein, & A. Gruzman, Covered by Neuroligin-2-derived peptide polyamidoamine-based (PAMAM) dendrimers enhances pancreatic β-cells proliferation and functions, MedChemComm, Ahead of print, Dec 12th, 2018

תחומי מחקר

Magnetic and non-magnetic nanoscale materials, conducting polymers, hybrid silica nanoparticles including UV-photoreactive nanosized composite materials, anti-bacterial nanoscale formulations, functional carbon nanotubes and controlled assemblies, surface modifications of nanomaterials using metal cation doping.

 

# Novel surface functionalizations based on electro-conductive polymers for the preparation of low-/medium density biochips, protein-based biosensors, and nanomaterials/magnetic nanosized composites - Application to cancer gene silencing using siRNA methodology

# Non-covalent chemical modifications of multi-walled/single-walled carbon nanotubes and applications to CNT-SELDI chips for diagnostic applications - Novel nanosized CNT-CP (conducting polymer) of designed morphology and chemical composition towards transparent conductive surfaces/polymeric coatings

# Templated synthesis of polypyrrolyl/polycarbazolyl functional polyCOOH nanorods for DNA sensing

# Chemically modified SiO2, SiC, TiO2, and SnO2 nanoparticles and related nanocomposites for scratch-resistant/super-hydrophobic sol-gel and polymeric surfaces/matrices

# Bimodal SiO2 nanoparticles for simultaneous FT-IR and fluorescence-based in vitro and in vivo imaging - Application to bimodal cancer imaging

# Nanotechnology-based surface chemistries for assembling of solid planar surfaces (SiO2, Au, and other noble metals)

# Photoreactive polymeric and non-polymeric nano(micro)particles for surface modification and nano(micro)structuration of polymeric films

# Development of innovative antibacterial nanoparticles for (i) environment-safe localized delivery of antibacterial active components and for (ii) anti-biofouling activity

# Aggregation control and surface modification of iron oxide (magnetite/maghemite) nanoparticles using a novel oxidative surface doping by cationic metallic cations

# Surface nanostructuration and chemical engineering of QCM sensing resonating crystals/electrodes for early cancer detection using acoustic non-contact methodologies

 

1.         Multifunctional Polymer Materials and Systems with Taylored Mechanical, Electrical and Optical Properties

2.         Water-Compatible Surface Modifications of PET [poly(ethylene-terephthalate] Fibers by Grafted PEG Polymers, and/or Conducting Polymers

3.         Smart Membrane for Hydrogen Energy Conversion: All Fuel Cell Functionalities in One Material

4.         Chemically Modified Multi-, Single-, and Double-Walled Carbon Nanotubes (MWCNTs, SWCNTs, & DWCNTs) for the Reinforcement of Polymeric Matrices and Surface Functionalization/Nanostructuration

5.         Nano-silencing in the cytoplasm and nucleus for killing of parasites and cancerous cells

6.         Surface modifications of dental implants using inorganic particles

7.         Functional bio-sensing nanostructured surfaces

8.         Parylene-based artificial smart lenses fabricated using a novel solid-on-liquid deposition process

9.         A Modular Active Nano-Platform for Advanced Cancer Management: Core Nanosystems, Tumor Targeting and Penetration, Molecular Imaging & Degradome-based Therapy