Prof. Rachel Lubart

Prof.
Prof. Rachel Lubart
Telephone: 
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  CURRICULUM VITAE

May 2013

NAME:                      Rachel Lubart

ADDRESS:                10 Hankin Street, Tel Aviv, Israel.

TEL. (work)              0544-566610

TEL. (home)              03-6055239

Email:             lubartr@mail.biu.ac.il

MARITAL STATUS:          Married, four children.

ACADEMIC EDUCATION: 1964-1968 - B.Sc. in Chem., Bar-Ilan University.

                                                1968-1970 - M.Sc., Molecular Spectroscopy, Department of Chemistry, Bar-Ilan University.

                                                1973-1978 - Ph.D., Depart of Chemistry, Bar-Ilan University. Doctoral Thesis: Energy levels of the benzene molecule in the vacuum U.V. Supervisors: Dr. M. Brit and Prof. H. Friedmann.

                                                1995-Lecturer,

                                                2003-Senior lecturer

                                                2012-Associate professor    

 

POST-GRADUATE STUDIES:

 

1980-1982 - Lasers in Chemistry, Department of Chemistry, Bar-Ilan Univ

1982-1984 - Photoacoustic Measurements, Dept. of Chemistry, Bar-Ilan Univ

1984-1985 - Single Crystal Growth, Dept. of Physics, Bar-Ilan Univ.         

1985 -1987- Electron Spin Resonance Measurements, Lasers in Medicine, Laser-  Tissue Interaction, Department of Physics, Bar-Ilan University.

 

AREAS OF EXPERTISE:

 

Molecular Spectroscopy, High Vacuum Techniques, Lasers in Chemistry, Photo-acoustic Measurements, Lasers in Medicine, E.S.R. (Electron Spin Resonance) Techniques, Laser-tissue Interaction, Photobiostimulation, Wound healing, Bacteria killing, Metal oxides nanoparticles.

                                               

 

           

SUPERVISION OF GRADUATE STUDENTS

Present: 2 M.Sc. students

                                   

           

 

Publications

 

Publications Since 2003

 

1. Ronit Lavi, Asher Shainberg, Harry Friedmann, Vladimir Shnevays  Ophra Rikover, Maor Eichler, Doron Kaplan and Rachel Lubart.(2003); Low Energy Visible Light Induces Reactive Oxygen Species Generation and Stimulates an Increase of Intracellular Calcium Concentration in Cardiac Cells. J Biol Chem. 2003; 278(42): 40917-22.       

 

 

2. Lavi R., Sinyakov M., Samuni A., Shatz S., Friedmann H., Shainberg A., Breitbart H., and Lubart R. ESR detection of 1O2 reveals enhanced redox activity in illuminated cell cultures. Free Radic. Res.38, 893-902. (2004).                                                                                                                                                    

 

3. Blotsky S., Lubart R., Avtalion R., Sinyakov M., and Lavie R. Visible light affects

chemiluminescence of carp (Cyprinis carpio) blood leukocytes. Photomedicine and Laser Surgery. 22, 265-268. (2004).                                                                                                                                         

       

4.  Zan-Bar T., Bartoov B., Segal R., Yehuda R., Lavi R., Lubart R., and  Avtalion R  

Influence of visible light and ultraviolet irradiation on motility and fertility of Mammalian and fish sperm. Photomed Laser Surg. 23, 549-55. (2005).                                                                                             

 

5. Lubart R., Eichler M., Lavi R., Friedmann H., and Shainberg A. Low-Energy

laser irradiation promotes cellular redox activity.(Invited review)  Photomedicine and Laser Surgery, 23, 3-9. (2005).      

 

6. Eichler M, Shainberg A, Lavie R and Lubart R.  Flavins are source of

visible-light-induced free radical formation in cells. Lasers Surg Med. 37, 14-9. (2005).    

 

7.  Lubart R., Kessler G, Lavi R., Friedmann H. Er:YAG laser promotes gingival wound repair by photo-dissociating water molecules. Photomed Laser Surg. 2005 Aug; 23 (4):369-72.                  

 

 8.  Lubart R., Lavi R., Friedman H., and Rochkind S., Photochemistry and Photobiology of light absorption by living cells (a mini review). Photomed Laser Surg. 2006 Apr;24(2):179-85.                          

 

 

9. M. Eichler, Ronit Lavi, Harry Friedmann, Asher Shainberg, and  R. Lubart.

Red light-induced redox reactions in cells observed with TEMPO. Photomed Laser Surg. 2007 Jun;25(3):170-4.

 

10. Sandro Belotsky, Michael S. Sinyakov, Helena M. Zhevelev, Bracha Shainberg,

R. Lubart, Harry Friedmann, and Ramy R. Avtalion Chemiluminescent analysis of light-irradiated leukocytes as a diagnostic tool for fast identification of pathological states. Photomed Laser Surg. 2007, 25(4):257-63                                    

   

11.Lubart R, Friedmann H, Lavie R, Longo L, Jacobi J, Baruchin O, Baruchin AM.  

A reasonable mechanism for visible light-induced skin rejuvenation. Lasers Med Sci. 2007 Mar;22(1):1-3.           

  

12. Lipovsky A, Nitzan Y, Lubart R. A possible mechanism for visible light-induced

 wound healing. Lasers Surg Med. 2008, 40(7):509-14.                                                       

 

13. Lipovsky A, Nitzan Y, Friedmann H, Lubart R. Sensitivity of Staphylococcus aurous

strains to broadband visible light. Photochem Photobiol. 2009, 85(1):255-60.                     

 

14. Guy Applerot, Anat Lipovsky, Rachel Dror, Nina Perkas, Yeshayahu Nitzan,

Rachel Lubart, Aharon Gedanken. Enhanced Antibacterial Activity of Nanocrystalline ZnO Is Due to Increased ROS-Mediated Cell Injury" Advanced Functional Mater. 19, 842-852 (2009).                   

 

15. Anat Lipovsky, Zeev Tzitrinovich, Harry Friedmann, Guy Applerot, Aharon Gedanken,

and Rachel Lubart. EPR study of visible light-induced ROS generation by nanoparticles of ZnO. J. Phys. Chem. C, 2009, 113 (36), pp 15997–16001.                                                                                          

 

16. Rinat Ankri, Harry Friedmann, Naphtali Savion, Shlomo Kotev -Emeth, Haim Breitbart, Rachel Lubart. Visible light induces NO formation in sperm and endothelial cells. Lasers Surg Med.42: 348-52 (2010).                                                    

 

17. Ronit Lavi, Asher Shainberg, Vladimir, Elicheva Hochauser, Ahuva Isaac, Tova Zinman, Harry Friedmann,  Rachel Lubart. Detailed Analysis of Reactive Oxygen Species Induced by Visible Light in Various Cell Types.  Lasers Surg Med. 42: 473-80 (2010).                                                                                                                 

 

18. Anat Lipovsky, Yeshayahu Nitzan, Aharon Gedanken and Rachel Lubart,  

Visible Light-Induced Killing of Bacteria as a Function of Wavelength: Implication for Wound Healing. Lasers in Surgery and Medicine 42:467–472 (2010).        

 

 

19.   Z. Landau, M. Migdal, A. Lipovsky and R. Lubart. Visible light-induced healing of

Diabetic or Venous foot ulcers: A placebo-controlled double blind study. Photomedicine and Laser Surgery. 2011 Jan 9 (2011

 

20.    Ankri, R., Lubart, R. and Taitelbaum, H. Estimation of the optimal wavelengths for laser-induced wound healing. Lasers in Surgery and Medicine; 42(8):760-4 (2010).             

21. Sharon Elad, Noa Luboshitz, Tehila Cohen, Elad Wainchwaig Michael Shapira, Igor Resnick, 

Ruth Radiano, Rachel Lubart, Reuven Or. A Randomized Controlled Trial of Visible-Light Therapy For The Prevention of Oral Mucositis. Oral Oncology  47(2):125-30 (2011).                                                                                         

 

22. Anat Lipovsky, Aharon Gedanken, Yeshayahu Nitzan  and Rachel Lubart. Enhanced inactivation of bacteria by metal-oxide nanoparticles combined with visible light irradiation. (Invited paper). Lasers Surg Med. 43(3): 236-240. (2011).      23 Anat Lipovsky, Yeshayahu Nitzan, Aharon Gedanken, and Rachel Lubart. Antifungal activity of ZnO nanoparticles-the role of ROS mediated cell injury. Nanotechnology. 22(10): 105101. (2011).                                                         

A note from the publisher: Your article has been downloaded 250 times!
 

24. Shahar S, Wiser A, Ickowicz D, Lubart R, Shulman A, Breitbart H. Light-mediated activation reveals a key role for protein kinase A and sarcoma protein kinase in the development of sperm hyper-activated motility. Hum Reprod. 26(9):2274-82. (2011).                                                                                                               

 

25. Yana Reznick, Ehud Banin, Anat Lipovsky, Rachel Lubart and Zeev Zalevsky. Direct laser light enhancement of susceptibility of bacteria to gentamicin antibiotic. Optics communications. 284 (1): 5501-5507 . (2011)

 

 

26. R. Lavi, R Ankri, M.Sinyakov, M. Eichler, H Friedmann, A Shainberg, H. Breitbart, and R. Lubart. The Plasma Membrane is Involved in the Visible Light – Tissue Interaction. Accepted for publication in Photomed Laser Surg. (2011).

 

27.  A. Lipovsky, L. levitski, Z. Tzitrinovich, A. Gedanken and R. Lubart. (2011) The different behavior of Rutile and Anatase nanoparticles in forming oxy radicals upon illumination with visible light: An EPR study. Accepted for publication in Photochemistry and Photobiology.  (2011

 

28.  R. Lubart, A. M. Baruchin , R. Lavie and H. Friedmann. A novel explanation for the healing effect of Er: YAG laser during skin rejuvenation. Journal of Cosmetic and Laser Therapy. 13(1):33-4. (2011).                                                                            

  

29. D. Fixler, R. Ankri, H. Duadi, R. Lubart, Z. Zalevsky. Depolarization of light in biological tissues. Optics and Lasers in Engineering. 50: 850–854. (2012).   I.F 1.6


30. G. Applerot, E.Banin, J.Lellouche, A.Lipovsky, Y.Nitzan, R.Lubart, A. Gedanken. Understanding the Antibacterial Mechanism of CuO Nanoparticles: Revealing the Route of Induced Oxidative Stress. Small. 2012 Nov 5;8(21):3326-37. (2012)

 

     

Proceedings

R. Lubart, A. Lipovski  and A. Gedanken. The use of visible light and metal oxide nano particles for pathogen inactivation. To be published in Lasers in Medical Sciences 2012.

  Y. Reznick, E Banin, A Lipovsky, R.  Lubart and Z. Zalevsky. Laser based enhancement of susceptibility of bacteria to antibiotic. Biophotonics and Immune  Responses VII. Edited by Chen, Wei R. Proceedings of the SPIE, Volume 8224, pp. 82240K-82240K-10 (2012).

 

 

           Letters to the Editor

Lubart R., Lavi R., Friedmann H. The penetration of white light through human tissue. Photomed and Laser Surg. 23(4):435-6.(2005

 

Lubart R. Low level laser therapy is not low. Photomed Laser Surg. Aug;24(4):532. (2006)         IF  1.75

                                                                                                                             

 

R. Lubart. A possible mechanism for treating Staphylococcus aureus induced chronic Osteomyelitis in rats using 808nm light. A letter to the editor. Photomed Laser Surg.  29(12):789-90. (2011).

                                                                                       

     R. Lubart and H. Friedmann. LLLT and PDT. Letter to the editor,

    Laser Therapy, 20(3), 233. (2011).

 

 

          Editorial                R. Lubart. (Invited Editorial) Metal-oxide nano particles increases the bactericidal       effect of blue light. To be published in Photomedicine and Laser Surgery. 2012  

 

 

            

 

 

 

 

           מאמרים ופרקים בספרים                                     Articles and Chapters in Books

1.      R. Lubart (Invited chapter). Visible light – sperm cell interaction, Nova Science Publishers, Human Spermatozoa: Maturation, Capacitation and Abnormalities, Editors: Thomas Lejeune and Pascal Delvaux. Chapter 22.

2.      Maor Eichler, Asher Shainberg, Abe M. Baruchin, and Rachel Lubart. New light on the mechanism of visible light therapy. Nova Science Publishers, Inc., To be published.

 

 

 

Patents

S. Rochkind and R. Lubart: Apparatus for inducing regeneration of nerve fibers at an injured  side of the spinal cord. US Patent No. 4,966,144 (1990)

R. Lubart. Device for light irradiation into tissue.  US  Patent No.6,379,376 (2002).

R. Lubart. Light device for improving sperm fertilization capability. US patent no. 6,379,939 (2002)

R. Lubart.  Method for cell activation and tissue repair using nanoparticles and light, 2010 (Provisional)

R. Lubart. A light device for pain relief. 2010 (Provisional)

R. Lubart. Method and device for visible light induced phototoxic effect on mammalian cells and microorganisms. 2010 (Provisional)

A. Gedanken, R. Lubart, A. Lipovsky, N. Perkas, Y. Nitzan. Coating Artificial nails with Metal Oxide Nanoparticles for Producing  Antimicrobial nails. 2010 (Provisional)

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Patents

S. Rochkind and R. Lubart: Apparatus for inducing regeneration of nerve fibers at an injured  side of the spinal cord. US Patent No. 4,966,144 (1990)

R. Lubart. Device for light irradiation into tissue.  US  Patent No.6,379,376 (2002).

R. Lubart. Light device for improving sperm fertilization capability. US patent no. 6,379,939 (2002)

R. Lubart.  Method for cell activation and tissue repair using nanoparticles and light, 2010 (Provisional)

R. Lubart. A light device for pain relief. 2010 (Provisional)

R. Lubart. Method and device for visible light induced phototoxic effect on mammalian cells and microorganisms. 2010 (Provisional)

A. Gedanken, R. Lubart, A. Lipovsky, N. Perkas, Y. Nitzan. Coating Artificial nails with Metal Oxide Nanoparticles for Producing  Antimicrobial nails. 2010 (Provisional)